| Intrigue | 1947 |
| Lady Jane
Lady Jane Grey | 1985 |
 | Room with a View
Lucy Honeychurch | 1986 |
| Maurice
Lady at Cricket Match | 1987 |
| Hazard of Hearts | 1987 |
| Mask | 1988 |
| Getting It Right
Minerva Munday | 1989 |
| Francesco | 1989 |
| Hamlet
Ophelia | 1990 |
| Howard's End
Helen Schlegel | 1992 |
| Dancing Queen
Pandora / Julie (as Helena Bonham-Carter) | 1993 |
 | Mary Shelley's Frankenstein
Elizabeth | 1994 |
| Mighty Aphrodite
Amanda | 1995 |
| Margaret's Museum
Margaret MacNeil | 1995 |
| Portraits Chinois
Ada | 1996 |
| Dark Adapted Eye | 1996 |
| Keep the Aspidistra Flying
Rosemary | 1997 |
| Merlin
Morgan Le Fay | 1998 |
 | Wings of the Dove
Kate | 1998 |
| Fight Club
Marla Singer | 1999 |
 | Planet of the Apes
Ari | 2001 |
 | Novocaine
Susan Ivey | 2002 |
| Big Fish
Jenny/The Witch | 2003 |
| Lemony Snicket's A Series of Unfortunate Events
Beatrice Baudelaire | 2004 |
| Charlie and the Chocolate Factory
Mrs Bucket | 2005 |
 | Wallace & Gromit: The Curse of the Were-Rabbit
Lady Campanula Tottington | 2005 |
| Corpse Bride
Voice: Corpse Bride | 2005 |
| Conversations with Other Women
Woman | 2005 |
 | Sweeney Todd: The Demon Barber of Fleet
Mrs Lovett | 2007 |
 | Harry Potter and the Order of the Phoenix
Bellatrix Lestrange | 2007 |
 | Harry Potter and the Half-Blood Prince
Bellatrix Lestrange | 2009 |
| Terminator Salvation
Serena | 2009 |
| Enid Blyton
Enid Blyton | 2009 |
 | King's Speech
Queen Elizabeth | 2010 |
 | Harry Potter and the Deathly Hallows Part 1
Bellatrix Lestrange | 2010 |
 | Alice in Wonderland
The Red Queen | 2010 |
 | Harry Potter and the Deathly Hallows Part 2
Bellatrix Lestrange | 2011 |
 | Dark Shadows
Dr. Julia Hoffman | 2012 |
 | Les Misérables
Madame Thénardier | 2012 |
 | Lone Ranger
Red Harrington | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair
( Photo Diary ) | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Young and Prodigious T.S. Spivet
Dr. Clair, T.S. Spivet's Mother | 2013 |
 | Cinderella
Fairy Godmother | 2015 |
 | Alice Through the Looking Glass
Red Queen | 2016 |
| Sgt. Stubby: An American Hero
Margaret Conroy (voice) | 2018 |
 | Ocean's Eight
Rose Weil | 2018 |
 | Enola Holmes
Eudoria Holmes | 2020 |